If you are pregnant or thinking about becoming pregnant, talk with your doctor about ways to increase your chances of having a healthy baby. CDC funds the Centers for Birth Defects Research and Prevention, which collaborate on large studies such as the National Birth Defects Prevention Study (NBDPS births 1997-2011) and the Birth Defects Study To Evaluate Pregnancy exposureS (BD-STEPS began with births in 2014), to understand the causes of and risks for birth defects, including anophthalmia and microphthalmia.ĬDC continues to study birth defects, such as anophthalmia and microphthalmia, and how to prevent them. Understanding the factors that are more common among babies with a birth defect will help us learn more about the causes. Like many families of children with a birth defect, CDC wants to find out what causes them. These defects might also be caused by a combination of genes and other factors, such as the things the mother comes in contact with in the environment or what the mother eats or drinks, or certain medicines she uses during pregnancy. These medicines can lead to a pattern of birth defects, which can include anophthalmia or microphthalmia. Anophthalmia and microphthalmia can also be caused by taking certain medicines, like isotretinoin (Accutane®) or thalidomide, during pregnancy. Some babies have anophthalmia or microphthalmia because of a change in their genes or chromosomes. The causes of anophthalmia and microphthalmia among most infants are unknown. Researchers estimate that about 1 in every 5,200 babies is born with anophthalmia/microphthalmia in the United States. How Many Babies are Born with Anophthalmia/Microphthalmia? Anophthalmia and microphthalmia often result in blindness or limited vision. Click here to view a larger image What is Anophthalmia and Microphthalmia?Īnophthalmia and microphthalmia develop during pregnancy and can occur alone, with other birth defects, or as part of a syndrome.
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